Vela

frontiers / frontier

AI-for-science benchmark state

constellation seal · derived from vfr_efc649fd772a1ff1
id
vfr_efc649fd772a1ff1
license
CC-BY-4.0
findings
12
accepted core
12
contested
0
links
0
sources
1
evidence
12
avg conf
0.30

used by 0 · replayed by 1 producer · second seat open

e24/24 · finding.noted · reviewer:will-blair · 2026-06-10 · 6c12→d02f

Evidence atom

back to sources

BENCHMARK CLAIM (ProteinGym) — EVE (evolutionary VAE over an MSA) REPORTS strong variant-effect prediction, especially for clinical variants. VERIFICATION STATE: author-reported; fully MSA-dependent; per-protein model fitting. NOT re-run here. Open obligation: re-fit on pinned MSAs and confirm the held-out assay Spearman.

id
vea_701b8b3ab51f97af
frontier
AI-for-science benchmark state
source
vs_066123dd29a9c5b4
finding
vf_cc50639072ba1867

evidence boundary

unknown

computational

finding binding

bound

computational

BENCHMARK CLAIM (ProteinGym) — EVE (evolutionary VAE over an MSA) REPORTS strong variant-effect prediction, especially for clinical variants. VERIFICATION STATE: author-reported; fully MSA-dependent; per-protein model fitting. NOT re-run here. Open obligation: re-fit on pinned MSAs and confirm the held-out assay Spearman.

source binding

source-bound

manual finding

vs_066123dd29a9c5b4

review context

unverified

2 events

2 reviewable changes and 0 evaluation records target this atom or its bound objects.

statement

BENCHMARK CLAIM (ProteinGym) — EVE (evolutionary VAE over an MSA) REPORTS strong variant-effect prediction, especially for clinical variants. VERIFICATION STATE: author-reported; fully MSA-dependent; per-protein model fitting. NOT re-run here. Open obligation: re-fit on pinned MSAs and confirm the held-out assay Spearman.

extraction method

manual_curation

support relation

unknown

condition refs

vcnd_922db3d676f1352f

caveats

  • missing evidence locator

Review, event, and evaluation records

4

events

  • vev_270eaf05963c65dffinding.noted

    HARDENING (benchmark-state): label_provenance=attested (records-not-reruns; ground truth is an answer key, not a frozen-verifier rederivation), valid_as_of=2026-06-10, model_cutoff=unknown. Under the trust ladder, attested label provenance caps this record below 'verified' until a deterministic rederivation exists.

    reviewer:will-blairreviewer:will-blair · 2026-06-10

  • vev_bd0ec86a1be50d66finding.asserted

    Manual finding added to frontier state

    reviewer:will-blairreviewer:will-blair · 2026-06-10

reviewable changes

  • vpr_74c27456b2783c8dfinding.note

    HARDENING (benchmark-state): label_provenance=attested (records-not-reruns; ground truth is an answer key, not a frozen-verifier rederivation), valid_as_of=2026-06-10, model_cutoff=unknown. Under the trust ladder, attested label provenance caps this record below 'verified' until a deterministic rederivation exists.

    agent — machine actor, no signing keyapplied · agent:hardening-2026-06-10 · 2026-06-10

  • vpr_be9c7dcdf52b3be5finding.add

    Manual finding added to frontier state

    reviewer:will-blairapplied · reviewer:will-blair · 2026-06-10

evaluations

No evaluation rows are attached.

statement.registered · agent:claude-proxy · 4 days

renders the record as of vev_e73c9b6c · 1,355 events · hub

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