source boundary
frontier-owneddeclared
A source record is provenance. It supports a finding only through evidence atoms, extraction spans, and reviewed finding bundles.
frontiers / frontier
Source record
back to sourcessource boundary
frontier-ownedA source record is provenance. It supports a finding only through evidence atoms, extraction spans, and reviewed finding bundles.
finding bindings
record contextFindings bound to this source through source ids, evidence atoms, provenance, or reviewed source-record slots.
evidence atoms
materializedEvidence atoms pin exact spans, measurements, selectors, or curation assertions to the source.
review context
inspectable1 reviewable changes and 0 evaluations are attached through this source or its findings.
Locator and citation
locator
title:Robbins et al. J Clin Oncol 2015 (NY-ESO-1 TCR); D'Angelo et al. Nat Med 2024 (afami-cel SPEARHEAD-1)
imported
2026-05-09T22:25:02.277468+00:00
extraction mode
manual_curation
authors
agent:immuno-research-bot-2026-05-09
Caveats
No source-specific caveats are recorded.
Adoptive transfer of T-cell receptor (TCR)-engineered T cells targeting NY-ESO-1 produced durable responses in HLA-A*02:01-restricted patients with synovial sarcoma and metastatic melanoma; afami-cel (FDA approved 2024 for synovial sarcoma) extends precision T-cell therapy beyond CAR-T into MHC-restricted contexts.
events
vev_bd333acb821390b9finding.assertedManual finding added to frontier state
agent:immuno-research-bot-2026-05-09 · 2026-05-09
reviewable changes
vpr_c237dd8b4b207570finding.addManual finding added to frontier state
applied · agent:immuno-research-bot-2026-05-09 · 2026-05-09
evaluations
No evaluation rows are attached.