Proposed change
reason
Exact NCI Thesaurus match for choroid plexus carcinoma; resolves entity-review debt without changing the finding assertion.
frontiers / frontier
Reviewable change
back to reviewChoroid plexus carcinoma (WHO grade 3) is rare and typically occurs in young children; treatment combines surgery with multi-agent chemotherapy and craniospinal radiation in older children. TP53 germline mutation evaluation is now standard given Li-Fraumeni association.
This is a proposal, not yet accepted frontier state. It names what it would change and who proposed it. Only an accepted review event, signed under reviewer authority, writes it into the frontier. Until then it carries no authority over the record.
Proposed change
reason
Exact NCI Thesaurus match for choroid plexus carcinoma; resolves entity-review debt without changing the finding assertion.
Provenance
proposed by
reviewer:solo-maintainer
actor type
human
created at
2026-05-21
target type
finding
Affected finding
inspect finding →Choroid plexus carcinoma (WHO grade 3) is rare and typically occurs in young children; treatment combines surgery with multi-agent chemotherapy and craniospinal radiation in older children. TP53 germline mutation evaluation is now standard given Li-Fraumeni association.
vf_e5f79a81a5f38ddeThe diff is computed against current frontier state, the same diff a reviewer reads before deciding.
The live diff is computed from a writable workspace. This frontier is read-only here, so the change is shown as recorded without a recomputed before / after.
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Pediatric high-grade glioma: distinct biology, distinct trials receives a reviewable source, finding, caveat, replication, evaluation, or proof-affecting edit.
The packet names affected record objects, evidence, rationale, reviewer-facing fields, and expected proof impact.
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