Proposed change
reason
v0.344 solo-maintainer pediatric entity-resolution wave: exact public identifier match for unresolved entity; clears needs_review without changing the assertion.
frontiers / frontier
Reviewable change
back to reviewPediatric ATRT subgroups (TYR, MYC, SHH defined by methylation) require subgroup-stratified treatment intensity; younger ATRT patients with MYC subgroup or metastatic disease have particularly poor prognosis and high-dose chemotherapy + autologous stem-cell rescue is a frequent approach without consensus standard-of-care.
This is a proposal, not yet accepted frontier state. It names what it would change and who proposed it. Only an accepted review event, signed under reviewer authority, writes it into the frontier. Until then it carries no authority over the record.
Proposed change
reason
v0.344 solo-maintainer pediatric entity-resolution wave: exact public identifier match for unresolved entity; clears needs_review without changing the assertion.
Provenance
proposed by
reviewer:solo-maintainer
actor type
human
created at
2026-05-20
target type
finding
Affected finding
inspect finding →Pediatric ATRT subgroups (TYR, MYC, SHH defined by methylation) require subgroup-stratified treatment intensity; younger ATRT patients with MYC subgroup or metastatic disease have particularly poor prognosis and high-dose chemotherapy + autologous stem-cell rescue is a frequent approach without consensus standard-of-care.
vf_c618d66d61d5359dThe diff is computed against current frontier state, the same diff a reviewer reads before deciding.
The live diff is computed from a writable workspace. This frontier is read-only here, so the change is shown as recorded without a recomputed before / after.
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Pediatric high-grade glioma: distinct biology, distinct trials receives a reviewable source, finding, caveat, replication, evaluation, or proof-affecting edit.
The packet names affected record objects, evidence, rationale, reviewer-facing fields, and expected proof impact.
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