record state
frontier-ownedReview status
This finding is part of accepted frontier state. Review events, reviewable changes, and proof state explain how it can change.
unreviewed
frontiers / frontier
Finding bundle
back to stateno incoming links yet
record state
frontier-ownedThis finding is part of accepted frontier state. Review events, reviewable changes, and proof state explain how it can change.
finding statement
finding type[object Object] · [object Object] · [object Object] · [object Object]
evidence
source-boundexperimental · manual state transition; control details require source inspection
proof impact
packet context5 reviewable changes and 0 evaluation records are attached to this finding id.
Evidence and conditions
method
manual state transition; control details require source inspection
evidence type
experimental
conditions
Provenance
source title
Hargrave et al. Lancet Oncol 2023; Bouffet et al. NEJM 2023 (FIREFLY-2)
authors
agent:phgg-research-bot-2026-05-09
Pediatric BRAF-V600E-positive low-grade gliomas respond strongly to dabrafenib + trametinib combination, with phase 3 superiority over carboplatin + vincristine in the FIREFLY-2 program; combined BRAF/MEK inhibition is now first-line for BRAF V600E pediatric LGG.
vs_3e5daa3d1817889c · manual_curation
outgoing
No outgoing links.
incoming
No incoming links.
events
vev_1b958b90141022b1finding.entity_resolvedv0.351 solo-maintainer brain-tumor translation wave: exact public identifier match; clears needs_review without changing the assertion.
reviewer:solo-maintainer · 2026-05-21
vev_6bf55afe53aa8b28finding.entity_resolvedv0.351 solo-maintainer brain-tumor translation wave: exact public identifier match; clears needs_review without changing the assertion.
reviewer:solo-maintainer · 2026-05-21
vev_820b6e7643ba403efinding.entity_resolvedv0.351 solo-maintainer brain-tumor translation wave: exact public identifier match; clears needs_review without changing the assertion.
reviewer:solo-maintainer · 2026-05-21
vev_8c9112b2559998d6finding.assertedManual finding added to frontier state
agent:phgg-research-bot-2026-05-09 · 2026-05-09
vev_b327d2cbe885cb21finding.entity_resolvedv0.351 solo-maintainer brain-tumor translation wave: exact public identifier match; clears needs_review without changing the assertion.
reviewer:solo-maintainer · 2026-05-21
reviewable changes
vpr_6ed1ad3ccba58517finding.entity_resolvev0.351 solo-maintainer brain-tumor translation wave: exact public identifier match; clears needs_review without changing the assertion.
applied · reviewer:solo-maintainer · 2026-05-21
vpr_b76ff1cf926da70afinding.entity_resolvev0.351 solo-maintainer brain-tumor translation wave: exact public identifier match; clears needs_review without changing the assertion.
applied · reviewer:solo-maintainer · 2026-05-21
vpr_b8d952f24d184567finding.entity_resolvev0.351 solo-maintainer brain-tumor translation wave: exact public identifier match; clears needs_review without changing the assertion.
applied · reviewer:solo-maintainer · 2026-05-21
vpr_b956ab6bd1641a77finding.entity_resolvev0.351 solo-maintainer brain-tumor translation wave: exact public identifier match; clears needs_review without changing the assertion.
applied · reviewer:solo-maintainer · 2026-05-21
vpr_dc8d6d94e7abf1d0finding.addManual finding added to frontier state
applied · agent:phgg-research-bot-2026-05-09 · 2026-05-09
evaluations
No evaluation record targets this finding id.