record state
frontier-ownedReview status
This finding is part of accepted frontier state. Review events, reviewable changes, and proof state explain how it can change.
unreviewed
frontiers / frontier
Finding bundle
back to stateno incoming links yet
record state
frontier-ownedThis finding is part of accepted frontier state. Review events, reviewable changes, and proof state explain how it can change.
finding statement
finding typeNo entity list is declared.
evidence
source-boundtheoretical · manual state transition
proof impact
packet context1 reviewable changes and 0 evaluation records are attached to this finding id.
Evidence and conditions
method
manual state transition
evidence type
theoretical
conditions
Provenance
source title
Revisiting pediatric HGGs and PNETs according to the WHO CNS5 criteria 2025 (10.1093/noajnl/vdaf175); Paediatric-type diffuse high-grade gliomas in the 5th CNS WHO Classification 2022 (10.32074/1591-951x-830)
authors
reviewer:will-blair
H3G34-mutant hemispheric gliomas presenting in infants and very young children may be histologically and clinically misclassified as 'infant-type hemispheric glioma' without molecular testing; however, WHO CNS5 classification now mandates H3F3A/H3.3 mutation testing to distinguish true H3G34-mutant cases requiring distinct treatment approaches.
vs_b59af407291c9215 · manual_curation
outgoing
vf_1607f129d5cdf5b0Distinction between genetic predisposition and H3G34 causation remains unsettled
incoming
No incoming links.
events
vev_b555cba9a3f74ce1finding.assertedManual finding added to frontier state
reviewer:will-blair · 2026-05-29
reviewable changes
vpr_578c3edcf1ae1bf1finding.addManual finding added to frontier state
applied · reviewer:will-blair · 2026-05-29
evaluations
No evaluation record targets this finding id.