record state
frontier-ownedReview status
This finding is part of accepted frontier state. Review events, reviewable changes, and proof state explain how it can change.
unreviewed
frontiers / frontier
Finding bundle
back to stateno incoming links yet
record state
frontier-ownedThis finding is part of accepted frontier state. Review events, reviewable changes, and proof state explain how it can change.
finding statement
finding type[object Object] · [object Object] · [object Object]
evidence
source-boundtheoretical · manual state transition; placebo-controlled clinical trial where source reports control arm · Homo sapiens
proof impact
packet context1 reviewable changes and 0 evaluation records are attached to this finding id.
Evidence and conditions
method
manual state transition; placebo-controlled clinical trial where source reports control arm
evidence type
theoretical
species
Homo sapiens
evidence spans
Reviewer gap scoped from Majzner et al. Nature 2022 DOI 10.1038/s41586-022-04489-4; ONC201 pediatric phase 1 registry NCT03416530; ONC201 recurrent DMG report PMID 38335473. Treat as review work, not a therapeutic recommendation.
curator_source
conditions
Provenance
source title
v0.301 pediatric HGG external-review depth wave
authors
reviewer:v0.301-depth
Reviewer gap scoped from Majzner et al. Nature 2022 DOI 10.1038/s41586-022-04489-4; ONC201 pediatric phase 1 registry NCT03416530; ONC201 recurrent DMG report PMID 38335473. Treat as review work, not a therapeutic recommendation.
vs_570e1f9185078850 · section:curator_source · manual_curation
outgoing
vf_86bc629e875ff052The v0.301 therapeutic-review gap depends on separating ONC201 response signals from unresolved comparative survival benefit.
incoming
No incoming links.
events
vev_9842df1e52f80af9finding.assertedManual finding added to frontier state
reviewer:v0.301-depth · 2026-05-14
reviewable changes
vpr_1526083161ab022cfinding.addManual finding added to frontier state
applied · reviewer:v0.301-depth · 2026-05-14
evaluations
No evaluation record targets this finding id.