record state
frontier-ownedReview status
This finding is part of accepted frontier state. Review events, reviewable changes, and proof state explain how it can change.
unreviewed
frontiers / frontier
Finding bundle
back to stateno incoming links yet
record state
frontier-ownedThis finding is part of accepted frontier state. Review events, reviewable changes, and proof state explain how it can change.
finding statement
finding typeNo entity list is declared.
evidence
source-boundtheoretical · manual state transition
proof impact
packet context1 reviewable changes and 0 evaluation records are attached to this finding id.
Evidence and conditions
method
manual state transition
evidence type
theoretical
conditions
Provenance
source title
Real-world Japanese C-CAT database analysis; n=114 diffuse midline glioma patients
authors
reviewer:will-blair
Blood-based liquid biopsy (FoundationOne Liquid CDx) shows critically limited sensitivity (2.8%) for H3K27M mutation detection in DMG compared to tissue-based comprehensive genomic profiling (92.2% with FoundationOne CDx), restricting clinical biomarker utility for therapy monitoring.
vs_e6fd7fc5dafe75d5 · manual_curation
outgoing
vf_b9d6c5c40b15e0c2Liquid biopsy limitations preclude non-invasive mutation tracking for biomarker-driven dosing
incoming
No incoming links.
events
vev_a83d79695b496221finding.assertedManual finding added to frontier state
reviewer:will-blair · 2026-05-29
reviewable changes
vpr_eda91d5c36a34047finding.addManual finding added to frontier state
applied · reviewer:will-blair · 2026-05-29
evaluations
No evaluation record targets this finding id.