source boundary
frontier-owneddeclared
A source record is provenance. It supports a finding only through evidence atoms, extraction spans, and reviewed finding bundles.
frontiers / frontier
Source record
back to sourcessource boundary
frontier-ownedA source record is provenance. It supports a finding only through evidence atoms, extraction spans, and reviewed finding bundles.
finding bindings
record contextFindings bound to this source through source ids, evidence atoms, provenance, or reviewed source-record slots.
evidence atoms
materializedEvidence atoms pin exact spans, measurements, selectors, or curation assertions to the source.
review context
inspectable1 reviewable changes and 0 evaluations are attached through this source or its findings.
Locator and citation
locator
title:G207 phase I pediatric high-grade glioma trial, New England Journal of Medicine
imported
2026-05-29T02:50:59.382039+00:00
extraction mode
manual_curation
authors
reviewer:will-blair
Caveats
No source-specific caveats are recorded.
observational · vf_5d212e0a9caf0c4e
Oncolytic HSV-1 G207 phase I pediatric HGG trial achieved 12.2-month median OS (5 of 12 patients >18 months survival) without dose-limiting toxicities—mechanism (lytic immunity + oncolytic spread) is distinct from chemotherapy and demonstrates mechanism-appropriate design necessity.
events
vev_d84e237bb0bb5896finding.assertedManual finding added to frontier state
reviewer:will-blair · 2026-05-29
reviewable changes
vpr_54a3b6bdf0aa18cefinding.addManual finding added to frontier state
applied · reviewer:will-blair · 2026-05-29
evaluations
No evaluation rows are attached.