source boundary
frontier-owneddeclared
A source record is provenance. It supports a finding only through evidence atoms, extraction spans, and reviewed finding bundles.
frontiers / frontier
Source record
back to sourcessource boundary
frontier-ownedA source record is provenance. It supports a finding only through evidence atoms, extraction spans, and reviewed finding bundles.
finding bindings
record contextFindings bound to this source through source ids, evidence atoms, provenance, or reviewed source-record slots.
evidence atoms
materializedEvidence atoms pin exact spans, measurements, selectors, or curation assertions to the source.
review context
inspectable1 reviewable changes and 0 evaluations are attached through this source or its findings.
Locator and citation
locator
title:Okubo et al. 2026 (10.1016/j.bbrc.2026.153471); Generation and multi-dimensional profiling of a childhood cancer cell line atlas 2023 (10.1016/j.ccell.2023.03.007)
imported
2026-05-29T02:50:58.097941+00:00
extraction mode
manual_curation
authors
reviewer:will-blair
Caveats
No source-specific caveats are recorded.
H3G34-mutant hemispheric gliomas exhibit robust upregulation of interferon-response genes and positive enrichment for multiple oncogenic signatures (Myc target genes, proliferation pathways); this interferon signature may contribute to immunotherapy resistance and differential tumor microenvironment composition.
events
vev_f0c351e7bb4c3459finding.assertedManual finding added to frontier state
reviewer:will-blair · 2026-05-29
reviewable changes
vpr_81973eea47ee6fc5finding.addManual finding added to frontier state
applied · reviewer:will-blair · 2026-05-29
evaluations
No evaluation rows are attached.