source boundary
frontier-owneddeclared
A source record is provenance. It supports a finding only through evidence atoms, extraction spans, and reviewed finding bundles.
frontiers / frontier
Source record
back to sourcessource boundary
frontier-ownedA source record is provenance. It supports a finding only through evidence atoms, extraction spans, and reviewed finding bundles.
finding bindings
record contextFindings bound to this source through source ids, evidence atoms, provenance, or reviewed source-record slots.
evidence atoms
materializedEvidence atoms pin exact spans, measurements, selectors, or curation assertions to the source.
review context
inspectable1 reviewable changes and 0 evaluations are attached through this source or its findings.
Locator and citation
locator
title:Bayliss et al. Sci Transl Med 2016; Pajtler et al. Acta Neuropathol 2018
imported
2026-05-09T22:21:56.921729+00:00
extraction mode
manual_curation
authors
agent:phgg-research-bot-2026-05-09
Caveats
No source-specific caveats are recorded.
Pediatric posterior fossa group A (PFA) ependymoma's CIMP-low signature reflects loss of the H3K27me3 repressive mark, partially analogous to (but mechanistically distinct from) H3K27M-mutant midline glioma; this convergence suggests common epigenetic vulnerabilities for therapeutic targeting.
events
vev_6e9617e080c92049finding.assertedManual finding added to frontier state
agent:phgg-research-bot-2026-05-09 · 2026-05-09
reviewable changes
vpr_b30251e06f95f3a8finding.addManual finding added to frontier state
applied · agent:phgg-research-bot-2026-05-09 · 2026-05-09
evaluations
No evaluation rows are attached.