source boundary
frontier-owneddeclared
A source record is provenance. It supports a finding only through evidence atoms, extraction spans, and reviewed finding bundles.
frontiers / frontier
Source record
back to sourcessource boundary
frontier-ownedA source record is provenance. It supports a finding only through evidence atoms, extraction spans, and reviewed finding bundles.
finding bindings
record contextFindings bound to this source through source ids, evidence atoms, provenance, or reviewed source-record slots.
evidence atoms
materializedEvidence atoms pin exact spans, measurements, selectors, or curation assertions to the source.
review context
inspectable1 reviewable changes and 0 evaluations are attached through this source or its findings.
Locator and citation
external sourcelocator
title:FDA accelerated approval, August 2025; Jazz Pharmaceuticals regulatory announcement
imported
2026-05-29T02:50:57.712249+00:00
extraction mode
manual_curation
authors
reviewer:will-blair
Caveats
No source-specific caveats are recorded.
therapeutic · vf_82179ae647552ad2
FDA grants accelerated approval to dordaviprone (August 6, 2025) for pediatric (age ≥1 year) and adult patients with progressive H3K27M-mutant DMG post-prior therapy, based on 20% objective response rate and durable disease control; first-ever systemic therapy approval for this indication.
events
vev_84010fb50e69a108finding.assertedManual finding added to frontier state
reviewer:will-blair · 2026-05-29
reviewable changes
vpr_de2b631f7b4db61bfinding.addManual finding added to frontier state
applied · reviewer:will-blair · 2026-05-29
evaluations
No evaluation rows are attached.