Proposed change
reason
Open need need_001 imported from artifact packet cap_9633575b0bead5b7
finding type
open_question
proposed confidence
0.40
confidence basis
agent-imported candidate claim; reviewer acceptance required
frontiers / frontier
Reviewable change
back to reviewWhich public patient-level dataset can jointly inspect amyloid clearance, tau movement, ARIA events, APOE4 status, and cognitive trajectory after anti-amyloid treatment?
This is a proposal, not yet accepted frontier state. It names what it would change and who proposed it. Only an accepted review event, signed under reviewer authority, writes it into the frontier. Until then it carries no authority over the record.
Proposed change
reason
Open need need_001 imported from artifact packet cap_9633575b0bead5b7
finding type
open_question
proposed confidence
0.40
confidence basis
agent-imported candidate claim; reviewer acceptance required
Provenance
proposed by
agent:scienceclaw-demo
actor type
agent
created at
2026-05-06
target type
finding
Affected finding
inspect finding →Which public patient-level dataset can jointly inspect amyloid clearance, tau movement, ARIA events, APOE4 status, and cognitive trajectory after anti-amyloid treatment?
vf_f62560b9a73eae49The diff is computed against current frontier state, the same diff a reviewer reads before deciding.
The live diff is computed from a writable workspace. This frontier is read-only here, so the change is shown as recorded without a recomputed before / after.
Canopus treats material changes like reviewable requests: one bounded packet, check output, reviewer decision, and accepted frontier effect.
Anti-amyloid translation in Alzheimer's disease receives a reviewable source, finding, caveat, replication, evaluation, or proof-affecting edit.
The packet names affected record objects, evidence, rationale, reviewer-facing fields, and expected proof impact.
Schema, provenance, benchmark, contradiction, and proof checks decide whether the request is ready to read.
A steward accepts, rejects, caveats, revises, or retracts the request under an inspectable identity.
Only the accepted event mutates frontier state. Atlases, constellations, and search update from that record state.