evidence boundary
supportsexperimental
An evidence atom is an inspectable support unit. It is not a finding by itself; it supports or challenges a finding through review.
frontiers / frontier
Evidence atom
back to sourcesevidence boundary
supportsAn evidence atom is an inspectable support unit. It is not a finding by itself; it supports or challenges a finding through review.
finding binding
boundAducanumab's EMERGE and ENGAGE phase 3 trials produced discordant efficacy results, making aducanumab a contested anti-amyloid translation precedent.
inspect finding →
source binding
source-boundvs_4d9acc27f5c5fd4f
inspect source →
review context
unverified3 reviewable changes and 0 evaluation records target this atom or its bound objects.
Evidence statement
Aducanumab's EMERGE and ENGAGE phase 3 trials produced discordant efficacy results, making aducanumab a contested anti-amyloid translation precedent.
locator
source:EMERGE and ENGAGE phase 3 trial records and FDA review materials|section:curator_source
extraction method
manual_curation
support relation
supports
condition refs
vcnd_113c91acac874107
Caveats
No evidence-specific caveats are recorded.
events
vev_a20df21281cce197finding.reviewedParallel phase 3 trials were discordant; preserve plural interpretation.
reviewer:will-blair-bot · 2026-05-06
vev_d5d58497546a1909finding.assertedManual finding added to frontier state
reviewer:will-blair-bot · 2026-05-06
vev_f99ca39b6d2e4067finding.confidence_revisedDiscordant phase 3 record lowers confidence in aducanumab as a stable translation anchor.
reviewer:will-blair-bot · 2026-05-06
reviewable changes
vpr_51af45c632c05070finding.reviewParallel phase 3 trials were discordant; preserve plural interpretation.
applied · reviewer:will-blair-bot · 2026-05-06
vpr_953ca8193cb056d3finding.confidence_reviseDiscordant phase 3 record lowers confidence in aducanumab as a stable translation anchor.
applied · reviewer:will-blair-bot · 2026-05-06
vpr_ccc97ca5ce161801finding.addManual finding added to frontier state
applied · reviewer:will-blair-bot · 2026-05-06
evaluations
No evaluation rows are attached.