record state
frontier-ownedReview status
This finding is part of accepted frontier state. Review events, reviewable changes, and proof state explain how it can change.
accepted
frontiers / frontier
Finding bundle
back to stateno incoming links yet
record state
frontier-ownedThis finding is part of accepted frontier state. Review events, reviewable changes, and proof state explain how it can change.
finding statement
finding typeNo entity list is declared.
evidence
source-boundobservational · manual state transition · Homo sapiens
proof impact
packet context2 reviewable changes and 0 evaluation records are attached to this finding id.
Evidence and conditions
method
manual state transition
evidence type
observational
species
Homo sapiens
evidence spans
A4 Study (NCT02008357) preclinical solanezumab arm halted 2020 after EXPEDITION3 + multi-cohort futility analysis; preclinical AD as solanezumab indication ruled out alongside mild-AD.
Cascade-densification deposit: Solanezumab EXPEDITION3 failure (Honig 2018) → broader anti-Aβ MAb scope refinement · curator_source · Cascade-densification deposit: Solanezumab EXPEDITION3 failure (Honig 2018) → broader anti-Aβ MAb scope refinement
conditions
Provenance
source title
Cascade-densification deposit: Solanezumab EXPEDITION3 failure (Honig 2018) → broader anti-Aβ MAb scope refinement
authors
reviewer:will-blair-bot
A4 Study (NCT02008357) preclinical solanezumab arm halted 2020 after EXPEDITION3 + multi-cohort futility analysis; preclinical AD as solanezumab indication ruled out alongside mild-AD.
vs_c06a1be73809d6e0 · source:Cascade-densification deposit: Solanezumab EXPEDITION3 failure (Honig 2018) → broader anti-Aβ MAb scope refinement|section:curator_source · manual_curation
outgoing
No outgoing links.
incoming
No incoming links.
events
vev_327adee886e476e1finding.assertedManual finding added to frontier state
reviewer:will-blair-bot · 2026-05-06
vev_94e4e6e8cd0dfa0dfinding.reviewedAccepted as a broad-frontier seed inside the anti-amyloid scope; source locator remains the authority.
reviewer:will-blair-bot · 2026-05-06
reviewable changes
vpr_12931a6601a7c828finding.reviewAccepted as a broad-frontier seed inside the anti-amyloid scope; source locator remains the authority.
applied · reviewer:will-blair-bot · 2026-05-06
vpr_fb13d9c46980221cfinding.addManual finding added to frontier state
applied · reviewer:will-blair-bot · 2026-05-06
evaluations
No evaluation record targets this finding id.