evidence boundary
unknownexperimental
An evidence atom is an inspectable support unit. It is not a finding by itself; it supports or challenges a finding through review.
frontiers / frontier
Evidence atom
back to sourcesevidence boundary
unknownAn evidence atom is an inspectable support unit. It is not a finding by itself; it supports or challenges a finding through review.
finding binding
boundMicrosatellite instability (MSI-H) and mismatch-repair deficiency (dMMR) are validated tissue-agnostic biomarkers for PD-1 inhibitor response; pembrolizumab gained FDA tissue-agnostic approval in 2017 for MSI-H solid tumors, demonstrating that biomarker-driven targeting can succeed across cancer types.
inspect finding →
source binding
source-boundvs_4c06f68305d4d47b
inspect source →
review context
unverified1 reviewable changes and 0 evaluation records target this atom or its bound objects.
Evidence statement
Microsatellite instability (MSI-H) and mismatch-repair deficiency (dMMR) are validated tissue-agnostic biomarkers for PD-1 inhibitor response; pembrolizumab gained FDA tissue-agnostic approval in 2017 for MSI-H solid tumors, demonstrating that biomarker-driven targeting can succeed across cancer types.
extraction method
manual_curation
support relation
unknown
condition refs
vcnd_5f006f24d47d489f
Caveats
events
vev_2f21af826c4ba233finding.assertedManual finding added to frontier state
agent:immuno-research-bot-2026-05-09 · 2026-05-09
reviewable changes
vpr_ee0d352cc378f53cfinding.addManual finding added to frontier state
applied · agent:immuno-research-bot-2026-05-09 · 2026-05-09
evaluations
No evaluation rows are attached.