evidence boundary
unknowntheoretical
An evidence atom is an inspectable support unit. It is not a finding by itself; it supports or challenges a finding through review.
frontiers / frontier
Evidence atom
back to sourcesevidence boundary
unknownAn evidence atom is an inspectable support unit. It is not a finding by itself; it supports or challenges a finding through review.
finding binding
boundONC201 phase I pediatric DMG/DIPG trial established pediatric-weight-scaled dosing (adult RP2D 625 mg scaled to body weight) with recommended phase II dose determination—adult oncology regimens require de novo pediatric pharmacokinetic/pharmacodynamic validation.
inspect finding →
source binding
source-boundvs_e69aeb00b1b9ef83
inspect source →
review context
unverified1 reviewable changes and 0 evaluation records target this atom or its bound objects.
Evidence statement
ONC201 phase I pediatric DMG/DIPG trial established pediatric-weight-scaled dosing (adult RP2D 625 mg scaled to body weight) with recommended phase II dose determination—adult oncology regimens require de novo pediatric pharmacokinetic/pharmacodynamic validation.
extraction method
manual_curation
support relation
unknown
condition refs
vcnd_4838f85060d00ef7
Caveats
events
vev_07a700809e50d72cfinding.assertedManual finding added to frontier state
reviewer:will-blair · 2026-05-29
reviewable changes
vpr_c9c2f49203860ed5finding.addManual finding added to frontier state
applied · reviewer:will-blair · 2026-05-29
evaluations
No evaluation rows are attached.