evidence boundary
unknowntheoretical
An evidence atom is an inspectable support unit. It is not a finding by itself; it supports or challenges a finding through review.
frontiers / frontier
Evidence atom
back to sourcesevidence boundary
unknownAn evidence atom is an inspectable support unit. It is not a finding by itself; it supports or challenges a finding through review.
finding binding
boundH3G34-mutant hemispheric gliomas exhibit constitutively elevated H3K36me3 (trimethylation at H3 lysine 36), which disrupts normal chromatin architecture and represses genes normally silenced by H3K27me3, creating an epigenetic state intermediate between wildtype and H3K27M-mutant tumors.
inspect finding →
source binding
source-boundvs_ce264e4fee4b4f7c
inspect source →
review context
unverified1 reviewable changes and 0 evaluation records target this atom or its bound objects.
Evidence statement
H3G34-mutant hemispheric gliomas exhibit constitutively elevated H3K36me3 (trimethylation at H3 lysine 36), which disrupts normal chromatin architecture and represses genes normally silenced by H3K27me3, creating an epigenetic state intermediate between wildtype and H3K27M-mutant tumors.
extraction method
manual_curation
support relation
unknown
condition refs
vcnd_43ad3a274298e0b3
Caveats
events
vev_e4a91253868b8ab3finding.assertedManual finding added to frontier state
reviewer:will-blair · 2026-05-29
reviewable changes
vpr_0307c4ea948a95f7finding.addManual finding added to frontier state
applied · reviewer:will-blair · 2026-05-29
evaluations
No evaluation rows are attached.