record state
frontier-ownedReview status
This finding is part of accepted frontier state. Review events, reviewable changes, and proof state explain how it can change.
unreviewed
frontiers / frontier
Finding bundle
back to staterecord state
frontier-ownedThis finding is part of accepted frontier state. Review events, reviewable changes, and proof state explain how it can change.
finding statement
finding typeNo entity list is declared.
evidence
source-boundtheoretical · manual state transition
proof impact
packet context1 reviewable changes and 0 evaluation records are attached to this finding id.
Evidence and conditions
method
manual state transition
evidence type
theoretical
conditions
Provenance
source title
H3-K27M-Mutant Nucleosomes Interact with MLL1 to Shape the Glioma Epigenetic Landscape (bioRxiv, 2021.08.09.455680)
authors
reviewer:will-blair
H3K27M recruits MLL1 methyltransferase at super-enhancer and promoter loci independently of PRC2 inhibition, suggesting parallel epigenetic programming via active H3K4me3 deposition that reinforces oncogenic gene expression in DIPG
vs_975d6bcb7d97d49d · manual_curation
outgoing
No outgoing links.
events
vev_cc342f016d1970c8finding.assertedManual finding added to frontier state
reviewer:will-blair · 2026-05-29
reviewable changes
vpr_05aecfd13eb0e2d4finding.addManual finding added to frontier state
applied · reviewer:will-blair · 2026-05-29
evaluations
No evaluation record targets this finding id.