record state
frontier-ownedReview status
This finding is part of accepted frontier state. Review events, reviewable changes, and proof state explain how it can change.
unreviewed
frontiers / frontier
Finding bundle
back to stateno incoming links yet
record state
frontier-ownedThis finding is part of accepted frontier state. Review events, reviewable changes, and proof state explain how it can change.
finding statement
finding type[object Object] · [object Object] · [object Object]
evidence
source-boundobservational · manual state transition
proof impact
packet context4 reviewable changes and 0 evaluation records are attached to this finding id.
Evidence and conditions
method
manual state transition
evidence type
observational
conditions
Provenance
source title
Mulhern et al. J Clin Oncol 2005; Merchant et al. Cancer 2009 (proton outcomes)
authors
agent:phgg-research-bot-2026-05-09
Cognitive late effects of pediatric brain-tumor treatment are dose-dependent and most severe in younger children; whole-brain radiation in patients under 5 years produces severe IQ decline, prompting strategies to defer or avoid radiation (proton therapy, methotrexate-based chemotherapy, autologous stem-cell rescue) where oncologically feasible.
vs_29ed57bf3b927139 · manual_curation
outgoing
No outgoing links.
incoming
No incoming links.
events
vev_5b3acc19acf3bb44finding.entity_resolvedExact MeSH match for radiotherapy; resolves entity-review debt without changing the finding assertion.
reviewer:solo-maintainer · 2026-05-20
vev_73597e1ddb1b8222finding.assertedManual finding added to frontier state
agent:phgg-research-bot-2026-05-09 · 2026-05-09
vev_8253b8a5ed660f5efinding.entity_resolvedExact MeSH match for medulloblastoma; resolves entity-review debt without changing the finding assertion.
reviewer:solo-maintainer · 2026-05-20
vev_ab031519903a7101finding.entity_resolvedMeSH Cognitive Dysfunction is the closest controlled heading for the cognitive late-effect entity in this finding; resolves the normalization flag without changing the evidence caveats or assertion.
reviewer:solo-maintainer · 2026-05-20
reviewable changes
vpr_02149000d02cb9e4finding.entity_resolveExact MeSH match for medulloblastoma; resolves entity-review debt without changing the finding assertion.
applied · reviewer:solo-maintainer · 2026-05-20
vpr_5c6af857a75849aefinding.entity_resolveMeSH Cognitive Dysfunction is the closest controlled heading for the cognitive late-effect entity in this finding; resolves the normalization flag without changing the evidence caveats or assertion.
applied · reviewer:solo-maintainer · 2026-05-20
vpr_6d3000db70843928finding.entity_resolveExact MeSH match for radiotherapy; resolves entity-review debt without changing the finding assertion.
applied · reviewer:solo-maintainer · 2026-05-20
vpr_d79c533c55cd3a8dfinding.addManual finding added to frontier state
applied · agent:phgg-research-bot-2026-05-09 · 2026-05-09
evaluations
No evaluation record targets this finding id.