source boundary
frontier-owneddeclared
A source record is provenance. It supports a finding only through evidence atoms, extraction spans, and reviewed finding bundles.
frontiers / frontier
Source record
back to sourcessource boundary
frontier-ownedA source record is provenance. It supports a finding only through evidence atoms, extraction spans, and reviewed finding bundles.
finding bindings
record contextFindings bound to this source through source ids, evidence atoms, provenance, or reviewed source-record slots.
evidence atoms
materializedEvidence atoms pin exact spans, measurements, selectors, or curation assertions to the source.
review context
inspectable4 reviewable changes and 0 evaluations are attached through this source or its findings.
Locator and citation
locator
title:Mulhern et al. J Clin Oncol 2005; Merchant et al. Cancer 2009 (proton outcomes)
imported
2026-05-09T22:03:49.008776+00:00
extraction mode
manual_curation
authors
agent:phgg-research-bot-2026-05-09
Caveats
No source-specific caveats are recorded.
Cognitive late effects of pediatric brain-tumor treatment are dose-dependent and most severe in younger children; whole-brain radiation in patients under 5 years produces severe IQ decline, prompting strategies to defer or avoid radiation (proton therapy, methotrexate-based chemotherapy, autologous stem-cell rescue) where oncologically feasible.
events
vev_5b3acc19acf3bb44finding.entity_resolvedExact MeSH match for radiotherapy; resolves entity-review debt without changing the finding assertion.
reviewer:solo-maintainer · 2026-05-20
vev_73597e1ddb1b8222finding.assertedManual finding added to frontier state
agent:phgg-research-bot-2026-05-09 · 2026-05-09
vev_8253b8a5ed660f5efinding.entity_resolvedExact MeSH match for medulloblastoma; resolves entity-review debt without changing the finding assertion.
reviewer:solo-maintainer · 2026-05-20
vev_ab031519903a7101finding.entity_resolvedMeSH Cognitive Dysfunction is the closest controlled heading for the cognitive late-effect entity in this finding; resolves the normalization flag without changing the evidence caveats or assertion.
reviewer:solo-maintainer · 2026-05-20
reviewable changes
vpr_02149000d02cb9e4finding.entity_resolveExact MeSH match for medulloblastoma; resolves entity-review debt without changing the finding assertion.
applied · reviewer:solo-maintainer · 2026-05-20
vpr_5c6af857a75849aefinding.entity_resolveMeSH Cognitive Dysfunction is the closest controlled heading for the cognitive late-effect entity in this finding; resolves the normalization flag without changing the evidence caveats or assertion.
applied · reviewer:solo-maintainer · 2026-05-20
vpr_6d3000db70843928finding.entity_resolveExact MeSH match for radiotherapy; resolves entity-review debt without changing the finding assertion.
applied · reviewer:solo-maintainer · 2026-05-20
vpr_d79c533c55cd3a8dfinding.addManual finding added to frontier state
applied · agent:phgg-research-bot-2026-05-09 · 2026-05-09
evaluations
No evaluation rows are attached.