record state
frontier-ownedReview status
This finding is part of accepted frontier state. Review events, reviewable changes, and proof state explain how it can change.
unreviewed
frontiers / frontier
Finding bundle
back to staterecord state
frontier-ownedThis finding is part of accepted frontier state. Review events, reviewable changes, and proof state explain how it can change.
finding statement
finding typeNo entity list is declared.
evidence
source-boundtheoretical · manual state transition
proof impact
packet context1 reviewable changes and 0 evaluation records are attached to this finding id.
Evidence and conditions
method
manual state transition
evidence type
theoretical
conditions
Provenance
source title
H3 K27M-altered glioma treatment landscape (Neuro-Oncology, S110/7475775)
authors
reviewer:will-blair
Patients with H3K27M-mutant DMG demonstrate median overall survival of 10.1-14.4 months from diagnosis, with 5-year survival <2%, compared to 54-60 Gy focal radiotherapy as the only standard-of-care intervention showing modest survival benefit
vs_a676a201a87f6724 · manual_curation
outgoing
vf_f6fd98935260314bONC201 + reirradiation improved OS to 22 months, a doubling of baseline survival, suggesting synergy
events
vev_6cd94038bd0b8190finding.assertedManual finding added to frontier state
reviewer:will-blair · 2026-05-29
reviewable changes
vpr_358a695956fbe0b5finding.addManual finding added to frontier state
applied · reviewer:will-blair · 2026-05-29
evaluations
No evaluation record targets this finding id.