record state
frontier-ownedReview status
This finding is part of accepted frontier state. Review events, reviewable changes, and proof state explain how it can change.
unreviewed
frontiers / frontier
Finding bundle
back to staterecord state
frontier-ownedThis finding is part of accepted frontier state. Review events, reviewable changes, and proof state explain how it can change.
finding statement
finding typeNo entity list is declared.
evidence
source-boundtheoretical · manual state transition
proof impact
packet context1 reviewable changes and 0 evaluation records are attached to this finding id.
Evidence and conditions
method
manual state transition
evidence type
theoretical
conditions
Provenance
source title
Pediatric HGG drug efflux transporter immunohistochemical and functional analysis
authors
reviewer:will-blair
Pediatric glioma express functionally active P-glycoprotein, MRP1, and BCRP transporters on tumor vasculature and glioma cells—adult-derived chemotherapies suffer attenuated CNS penetration via age-dependent blood-brain barrier efflux pump capacity.
vs_dc1f3992e2baaf0e · manual_curation
outgoing
vf_615dea30504e4ffeP-gp/BCRP efflux + CYP3A4 developmental maturation together explain pediatric-specific chemotherapy resistance
events
vev_5d82ba9b7bfcfceefinding.assertedManual finding added to frontier state
reviewer:will-blair · 2026-05-29
reviewable changes
vpr_676759197fa9d231finding.addManual finding added to frontier state
applied · reviewer:will-blair · 2026-05-29
evaluations
No evaluation record targets this finding id.