evidence boundary
supportsobservational
An evidence atom is an inspectable support unit. It is not a finding by itself; it supports or challenges a finding through review.
frontiers / frontier
Evidence atom
back to sourcesevidence boundary
supportsAn evidence atom is an inspectable support unit. It is not a finding by itself; it supports or challenges a finding through review.
finding binding
boundFDA accelerated approval of aducanumab (Aduhelm) June 2021 was contested at the FDA Advisory Committee (10-0 vote against, plus 1 uncertain); the surrogate-endpoint approval mechanism was used over Advisory Committee opinion. Three FDA AC members resigned in protest.
inspect finding →
source binding
source-boundvs_8da6a2f531df04ff
inspect source →
review context
unverified2 reviewable changes and 0 evaluation records target this atom or its bound objects.
Evidence statement
FDA accelerated approval of aducanumab (Aduhelm) June 2021 was contested at the FDA Advisory Committee (10-0 vote against, plus 1 uncertain); the surrogate-endpoint approval mechanism was used over Advisory Committee opinion. Three FDA AC members resigned in protest.
locator
source:Cascade-densification deposit: Aducanumab Phase Ib (Sevigny 2016) → ENGAGE/EMERGE controversy + scope flags|section:curator_source
extraction method
manual_curation
support relation
supports
condition refs
vcnd_a96fd120160742b0
Caveats
No evidence-specific caveats are recorded.
events
vev_a0c1a74912e3681cfinding.reviewedAccepted as a broad-frontier seed inside the anti-amyloid scope; source locator remains the authority.
reviewer:will-blair-bot · 2026-05-06
vev_f039c561f98f9930finding.assertedManual finding added to frontier state
reviewer:will-blair-bot · 2026-05-06
reviewable changes
vpr_0b31053ba6f0303dfinding.addManual finding added to frontier state
applied · reviewer:will-blair-bot · 2026-05-06
vpr_3fcd40e83d26271cfinding.reviewAccepted as a broad-frontier seed inside the anti-amyloid scope; source locator remains the authority.
applied · reviewer:will-blair-bot · 2026-05-06
evaluations
No evaluation rows are attached.