evidence boundary
unknowntheoretical
An evidence atom is an inspectable support unit. It is not a finding by itself; it supports or challenges a finding through review.
frontiers / frontier
Evidence atom
back to sourcesevidence boundary
unknownAn evidence atom is an inspectable support unit. It is not a finding by itself; it supports or challenges a finding through review.
finding binding
boundH3K27M-driven gliomas exploit dual PRC2-inhibition mechanisms via the K27M oncohistone itself and EZHIP (PFA ependymoma-associated protein), which directly contact EZH2 catalytic site in structurally parallel fashion and stabilize narrow H3K27me3 peaks at CpG islands
inspect finding →
source binding
source-boundvs_1fc2f41487432632
inspect source →
review context
unverified1 reviewable changes and 0 evaluation records target this atom or its bound objects.
Evidence statement
H3K27M-driven gliomas exploit dual PRC2-inhibition mechanisms via the K27M oncohistone itself and EZHIP (PFA ependymoma-associated protein), which directly contact EZH2 catalytic site in structurally parallel fashion and stabilize narrow H3K27me3 peaks at CpG islands
extraction method
manual_curation
support relation
unknown
condition refs
vcnd_9c9c727df5e7c4c0
Caveats
events
vev_514ecc6717f74858finding.assertedManual finding added to frontier state
reviewer:will-blair · 2026-05-29
reviewable changes
vpr_16ba5bc2fb0d2c02finding.addManual finding added to frontier state
applied · reviewer:will-blair · 2026-05-29
evaluations
No evaluation rows are attached.