evidence boundary
unknowntheoretical
An evidence atom is an inspectable support unit. It is not a finding by itself; it supports or challenges a finding through review.
frontiers / frontier
Evidence atom
back to sourcesevidence boundary
unknownAn evidence atom is an inspectable support unit. It is not a finding by itself; it supports or challenges a finding through review.
finding binding
boundH3.3K27M drives context-dependent activation of the CREB5/ID1 axis via super-enhancer remodeling, maintaining stem-like transcriptional states; CREB5 inhibition or KDM6B targeting restores H3K27me3 and suppresses stemness in H3K27M-mutant cells
inspect finding →
source binding
source-boundvs_3a7dc13a33032814
inspect source →
review context
unverified1 reviewable changes and 0 evaluation records target this atom or its bound objects.
Evidence statement
H3.3K27M drives context-dependent activation of the CREB5/ID1 axis via super-enhancer remodeling, maintaining stem-like transcriptional states; CREB5 inhibition or KDM6B targeting restores H3K27me3 and suppresses stemness in H3K27M-mutant cells
extraction method
manual_curation
support relation
unknown
condition refs
vcnd_49facdd4078551e7
Caveats
events
vev_1dbbac756b7a7eb4finding.assertedManual finding added to frontier state
reviewer:will-blair · 2026-05-29
reviewable changes
vpr_60a4a57ba1d6b2eefinding.addManual finding added to frontier state
applied · reviewer:will-blair · 2026-05-29
evaluations
No evaluation rows are attached.