record state
frontier-ownedReview status
This finding is part of accepted frontier state. Review events, reviewable changes, and proof state explain how it can change.
unreviewed
frontiers / frontier
Finding bundle
back to stateno incoming links yet
record state
frontier-ownedThis finding is part of accepted frontier state. Review events, reviewable changes, and proof state explain how it can change.
finding statement
finding type[object Object] · [object Object] · [object Object]
evidence
source-boundobservational · manual state transition
proof impact
packet context4 reviewable changes and 0 evaluation records are attached to this finding id.
Evidence and conditions
method
manual state transition
evidence type
observational
conditions
Provenance
source title
Zhukova et al. J Clin Oncol 2013; Waszak et al. Nature 2018 (germline TP53)
authors
agent:phgg-research-bot-2026-05-09
Pediatric SHH-medulloblastoma carrying TP53 mutations (germline or somatic) has poor prognosis distinct from sporadic SHH-medulloblastoma; this stratification is now standard in WHO 2021 and informs trial enrollment for Li-Fraumeni syndrome surveillance.
vs_169e023b6b2e5425 · manual_curation
outgoing
No outgoing links.
incoming
No incoming links.
events
vev_034755eea0b164f1finding.entity_resolvedExact NCBI Gene match for TP53; resolves entity-review debt without changing the finding assertion.
reviewer:solo-maintainer · 2026-05-20
vev_84fe1264ad385531finding.entity_resolvedExact MeSH match for medulloblastoma; resolves entity-review debt without changing the finding assertion.
reviewer:solo-maintainer · 2026-05-20
vev_855a5c8fa348fe2efinding.entity_resolvedExact NCBI Gene match for SHH; resolves pathway/entity-review debt without changing the finding assertion.
reviewer:solo-maintainer · 2026-05-20
vev_e5ce199aca875a76finding.assertedManual finding added to frontier state
agent:phgg-research-bot-2026-05-09 · 2026-05-09
reviewable changes
vpr_0653ea07892aaf1dfinding.entity_resolveExact MeSH match for medulloblastoma; resolves entity-review debt without changing the finding assertion.
applied · reviewer:solo-maintainer · 2026-05-20
vpr_122b9a0e42c69ad0finding.entity_resolveExact NCBI Gene match for SHH; resolves pathway/entity-review debt without changing the finding assertion.
applied · reviewer:solo-maintainer · 2026-05-20
vpr_a26c094cff505c76finding.entity_resolveExact NCBI Gene match for TP53; resolves entity-review debt without changing the finding assertion.
applied · reviewer:solo-maintainer · 2026-05-20
vpr_df503190d475f68efinding.addManual finding added to frontier state
applied · agent:phgg-research-bot-2026-05-09 · 2026-05-09
evaluations
No evaluation record targets this finding id.