source boundary
frontier-owneddeclared
A source record is provenance. It supports a finding only through evidence atoms, extraction spans, and reviewed finding bundles.
frontiers / frontier
Source record
back to sourcessource boundary
frontier-ownedA source record is provenance. It supports a finding only through evidence atoms, extraction spans, and reviewed finding bundles.
finding bindings
record contextFindings bound to this source through source ids, evidence atoms, provenance, or reviewed source-record slots.
evidence atoms
materializedEvidence atoms pin exact spans, measurements, selectors, or curation assertions to the source.
review context
inspectable4 reviewable changes and 0 evaluations are attached through this source or its findings.
Locator and citation
locator
title:Zhukova et al. J Clin Oncol 2013; Waszak et al. Nature 2018 (germline TP53)
imported
2026-05-09T22:21:54.537447+00:00
extraction mode
manual_curation
authors
agent:phgg-research-bot-2026-05-09
Caveats
No source-specific caveats are recorded.
Pediatric SHH-medulloblastoma carrying TP53 mutations (germline or somatic) has poor prognosis distinct from sporadic SHH-medulloblastoma; this stratification is now standard in WHO 2021 and informs trial enrollment for Li-Fraumeni syndrome surveillance.
events
vev_034755eea0b164f1finding.entity_resolvedExact NCBI Gene match for TP53; resolves entity-review debt without changing the finding assertion.
reviewer:solo-maintainer · 2026-05-20
vev_84fe1264ad385531finding.entity_resolvedExact MeSH match for medulloblastoma; resolves entity-review debt without changing the finding assertion.
reviewer:solo-maintainer · 2026-05-20
vev_855a5c8fa348fe2efinding.entity_resolvedExact NCBI Gene match for SHH; resolves pathway/entity-review debt without changing the finding assertion.
reviewer:solo-maintainer · 2026-05-20
vev_e5ce199aca875a76finding.assertedManual finding added to frontier state
agent:phgg-research-bot-2026-05-09 · 2026-05-09
reviewable changes
vpr_0653ea07892aaf1dfinding.entity_resolveExact MeSH match for medulloblastoma; resolves entity-review debt without changing the finding assertion.
applied · reviewer:solo-maintainer · 2026-05-20
vpr_122b9a0e42c69ad0finding.entity_resolveExact NCBI Gene match for SHH; resolves pathway/entity-review debt without changing the finding assertion.
applied · reviewer:solo-maintainer · 2026-05-20
vpr_a26c094cff505c76finding.entity_resolveExact NCBI Gene match for TP53; resolves entity-review debt without changing the finding assertion.
applied · reviewer:solo-maintainer · 2026-05-20
vpr_df503190d475f68efinding.addManual finding added to frontier state
applied · agent:phgg-research-bot-2026-05-09 · 2026-05-09
evaluations
No evaluation rows are attached.