record state
frontier-ownedReview status
This finding is part of accepted frontier state. Review events, reviewable changes, and proof state explain how it can change.
unreviewed
frontiers / frontier
Finding bundle
back to stateno incoming links yet
record state
frontier-ownedThis finding is part of accepted frontier state. Review events, reviewable changes, and proof state explain how it can change.
finding statement
finding typeNo entity list is declared.
evidence
source-boundtheoretical · manual state transition
proof impact
packet context1 reviewable changes and 0 evaluation records are attached to this finding id.
Evidence and conditions
method
manual state transition
evidence type
theoretical
conditions
Provenance
source title
DMG patient-derived culture m6A profiling and FTO inhibitor studies, 2026
authors
reviewer:will-blair
H3K27M-mutant DMG exhibits elevated m6A (N6-methyladenosine) enrichment on cell-motility transcripts; FTO inhibition induces S-phase arrest and downregulates cell cycle regulators, revealing epi-transcriptomic vulnerability orthogonal to H3K27M's chromatin effects.
vs_6c2e70d5b46df60d · manual_curation
outgoing
vf_35f210ebd4b1b2c4m6A dysregulation reveals epigenetic layer beyond H3K27 trimethylation impacted by histone mutation
incoming
No incoming links.
events
vev_dcb758885f6ae994finding.assertedManual finding added to frontier state
reviewer:will-blair · 2026-05-29
reviewable changes
vpr_8af4cf97695818bdfinding.addManual finding added to frontier state
applied · reviewer:will-blair · 2026-05-29
evaluations
No evaluation record targets this finding id.